Welcome to PLATO r32 !

PLATO is an easy-to-use polypharmacology predictive platform, designed for finding new putative protein drug targets and quantifying bioactivity affinity value.

PLATO user's guide

If you are satisfied, please cite us:

- Ciriaco, F; Gambacorta, N.; Trisciuzzi, D.; Nicolotti O. PLATO: A Predictive Drug Discovery Web Platform for Efficient Target Fishing and Bioactivity Profiling of Small Molecules. Int J Mol Sci. 2022,8, 5245.

- Ciriaco, F.; Gambacorta, N.; Alberga, D.; Nicolotti, O. Quantitative Polypharmacology Profiling Based on a Multifingerprint Similarity Predictive Approach. J.Chem. Inf. Model. 2021,61, 4868-4876.

- Alberga, D.; Trisciuzzi, D.; Montaruli, M.; Leonetti, F.; Mangiatordi, G.F.; Nicolotti, O. A new approach for drug target and bioactivity prediction: the Multifingerprint Similarity Search Algorithm (MuSSeL). J. Chem. Inf. Model. 2019, 59, 586–596.